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Tescan will be presenting at the Southeastern Microscopy Society (SEMS) meeting later this month.  Our presentation will be on a new optical imaging system we have recently developed.  Below i9s an abstract on the talk.

Live cell imaging is an integral component in better understanding cellular dynamics, for instance, differentiation, senescence, disease and death (such as apoptosis, necrosis, entosis), and external treatment. One key characteristic in observing cellular dynamics is a change in cellular morphology. Current cell imaging techniques lack several important components required for live cell imaging. For example, brightfield, phase contrast and differential interference contrast imaging all lack clear cell boundaries and quantitative data. Fluorescence imaging provides good boundary detection and quantitative data for segmentation, however, it is not a natural system (requires labeling) and has a high photo toxicity. Quantitative phase imaging (QPI) provides better boundary detection and quantitative data in a natural state. Imaging in scattering media (e.g. phospholipid emulsions, extracellular matrices) still presents an issue with in vitro observation of live cells. New patented technology of Coherence-controlled holographic microscopy allows for excellent boundary detection and quantitative data collection of live cells in scattering media. This allows for testing reactions of cells to a specific treatment. Examples include cancer cells and immune cells.

 

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